Judging a virus by its cover.

نویسندگان

  • Eva Szomolanyi-Tsuda
  • Raymond M Welsh
چکیده

The production of protective neutralizing antibodies occurs quickly in some viral infections but very slowly in others. In a new study, surface glycoproteins (the targets of neutralization) of 2 different viruses were genetically switched. Analysis of the neutralizing antibody response to each of the 2 parent and recombinant viruses in infected mice revealed that the speed of neutralizing antibody induction was intrinsically dependent on the surface glycoprotein and not the rest of the virus.

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 114 7  شماره 

صفحات  -

تاریخ انتشار 2004